According to the World Health Organization (WHO), a fungus that is genetically modified using genetic engineering can produce spider toxin to spam over 99 percent of the mosquitoes spreading malaria. Around 400,000 people are being killed when attacked by mosquitoes giving a direct result, malaria. This defoliation of human death by mosquitoes is recorded annually.
Several decades have passed still the routine way to curb malaria rests in the mosquito only. The use of insecticide also has failed to break the malaria parasite. Rather, healing the situation, mosquitoes have started to show resistance to insecticide and are surviving out of the poison. Scientists have decided to modify mosquitoes and other organisms that can eradicate mosquitoes genetically. Trials have already taken place in Burkina Faso. The results were almost perfect, where 99 percent of mosquitoes were killed within 45 days. The researchers say that their intention is not to extinct the insect genus but to curb the spreading of malaria worldwide. The researchers at the University of Maryland in the United States and the IRSS research institute in Burkina Faso identified a fungus known as Metarhizium pingshaense. This particular fungus naturally infects the Anopheles mosquitoes that contribute in spreading malaria.
Professor Raymond St Leger from the University of Maryland concluded that the next stage to stop the spread of malaria was to enhance the fungus as they are malleable and can be genetically modified, so it is easy to do this project. The researchers turned the toxin found in the venom of a funnel-web spider in Australia and instilled in the fungus itself. As a spider makes use of its fangs to pierce through the skin of insects and pour toxins, the fangs were then replaced by the genetically modified fungus. Laboratory tests proved that the fungus could kill quicker and used spores of few fungi to perform the job. The next step was to introduce the fungus into the world conditions as possible to ascertain its functionality.
Then, the fungal spores were added with the sesame oil and poured into white cotton sheets. The experiment was started with 1,500 mosquitoes. The sheets had the deadly fungus on which the mixture was added. After 45 days, only 13 mosquitoes were left after the spider-toxin fungus was used. The test is mosquito-specific only. It will not affect any other insect. The paper is to make some impudent steps to stop the spread of malaria. The fungus is serving as a hypodermic needle that using mosquito as its thread to weave onto. Hybrid is the name for the insecticide. The Environmental Protection Agency (EPA) has directly approved it, and the venom is derived from the Australian Blue Mountains funnel web-spider.
The control switch is the fungus itself. Several steps before this were taken to prevent malaria but could not succeed due to its high consensus for spreading from one place to another through the agent. By combining the genetic code, great results have been seen in the experiment stage. The process is under evaluation to bring before the world to curb malaria from spreading.